Patent File

Patent File 224 Cosmetics from lemongrass

No. Patent Number Title Abstract
1 WO 2010/018,526 Composition for treatment of the skin A natural composition comprising myrtle berries; seaweed; and at least two of tea tree oil, lemongrass oil, evening primrose oil, ginger, jojoba oil, neem oil, and chamomile, and uses thereof for treatment of skin conditions.
2 JPH 07,277,920 Cosmetic containing steam-distilled water and/or extract of lemongrass To effectively utilize steam-distilled water distilled away on a process for producing a lemongrass oil and a lemongrass extract for a cosmetic. CONSTITUTION:This cosmetic relates to steam-distilled water of a leaf or a stem of a lemongrass or a mixture thereof or/and a cosmetic containing an extract obtained by extraction with a water-soluble solvent. This stem-distilled water or cosmetic or both can be applied to all the forms of preparations (medicines, quasi-drugs, cosmetics, etc.). The cosmetic has high safety and an excellent fragrance and is capable of manifesting excellent effects on the skin and hair of the head.
3 CN 104,856,905 Hydrolat containing cymbopogon citratus The invention provides hydrolat containing cymbopogon citratus, which is prepared from the following raw materials in parts by weight: 15-20 parts of cymbopogon citratus extracting solution, 50-70 parts of deionized water, 5-7 parts of humectant, 5-8 parts of kiwi seed extracting solution and 1-3 parts of collagen extracting solution. The hydrolat is easy to absorb, has no irritation effect on skin, does not influence the recovery capability of the skin, and has effects of shrinking pores, balancing oil, moistening the skin and avoiding skin laxity and wrinkle.
4 CN 103,356,415 Lemon-grass essence cleansing nutritious emulsion The invention relates to a lemon-grass essence cleansing nutritious emulsion, belonging to the technical field of daily-use chemical cleaning care products. The lemon-grass essence cleansing nutritious emulsion is prepared by mixing the following substances according to a certain ratio: lemon-grass essence, natural marine polysaccharide, glycerol, polyethylene glycol, a foaming agent, Vitamin E oil and an emulgator. The lemon-grass essence cleansing nutritious emulsion has strong cleansing capacity, can effectively remove skin impurity, removes stubborn make-up mark, is mild, has no stimulation, takes the lemon-grass as a main component, contains rich vitamin C, eliminates edema and unnecessary fat, adjusts grease secretion, promotes blood circulation, nourishes skin and can be used for a long time to improve the skin.
5 CN 104,771,346 Lemongrass liquid soap and preparation method thereof The invention discloses a lemongrass liquid soap and a preparation method thereof. The liquid soap comprises the following raw materials in percentage by weight: 10 to 15% of lemongrass extract, 5 to 8% of glycerin, 0.5 to 0.8% of vitamin E, 2 to 5% of sodium chloride, 5 to 10% of pearl powder, 1 to 5% of lard, 1 to 3% of triethanolamine dodecyl sulfate, 1 to 3% of critic acid, and the balance being deionized water. The preparation method comprises the following steps: step one, preparing lemongrass extract; step two, weighing needed raw materials, mixing glycerin, lard, and triethanolamine dodecyl sulfate, stirring, and heating to obtain a mixture A; step two, mixing vitamin E, sodium chloride, critic acid, and deionized water, heating under stirring, adding lemongrass extract and pearl powder when the solution is still hot, stirring, and maintaining the temperature to obtain a mixture B; step four, adding the mixture A into the mixture B, and homogenizing to obtain the liquid soap. The preparation method is simple, and the liquid soap has a good effect on killing and inhibiting bacteria.
6 CN 104,323,941 Lemon-grass peppermint facial mask and preparation method thereof The invention discloses a lemon-grass peppermint facial mask and a preparation method thereof. The facial mask is prepared from the following components in percentage by mass: 11-12 percent of polyvinyl alcohol, 4.5-5 percent of propylene glycol, 4.5-5 percent of ethanol, 0.5-1 percent of vitamin E, 1-1.5 percent of jojoba oil, 0.8-1 percent of water-soluble azone, 0.4-0.6 percent of BP, 10-20 percent of lemon-grass extract, 10-15 percent of peppermint extract, 0.2 percent of essence and the balance of distilled water. The lemon-grass peppermint facial mask is capable of controlling oil and tightening pores, and remarkably improving acne, pimples and dark skin.
7 CN 104,940,051 Lemon-grass perfume The invention discloses a lemon-grass perfume which is characterized by comprising the following volume components: basic essential oil, an essential oil emulsifier and 95% ethanol which is added until the total amount is 100 parts. The lemon-grass perfume disclosed by the invention takes lemon-grass volatile oil extracted from lemon-grass as a main component, and has obvious oxidation resistance, antibacterial property and antivirus property, the obtained perfume has a delicate aroma of lemon, and the aroma is harmonious and natural and lasts for a long time, so that the lemon-grass perfume has a very high application value and a broad market prospect.
8 CN 104,862,130 Preparation method of cymbopogon citratus handmade soap The invention provides a preparation method of a cymbopogon citratus handmade soap. The preparation method comprises the following steps: preparing the following raw materials in parts by weight: 20-30 parts of cymbopogon citratus, 50-60 parts of a transparent soap base, 10-13 parts of glycerol, and 1-3 parts of synergetic essential oil; selecting the fresh cymbopogon citratus leaves, cleaning the leaves clearly, adding 5-10 times of clear water, boiling for 1-3 hours with soft fire at the temperature of 90-120 DEG C, filtering, and taking the filtrate to obtain the cymbopogon citratus liquid; placing the transparent soap base into a glass container, heating the glass container at the temperature of 40-60 DEG C under the water insulation condition, and stirring to enable the transparent soap base to be completely molten; adding the cymbopogon citratus liquid obtained in the step 2, and the other raw materials of glycerol and the synergetic essential oil into the molten transparent soap base, uniformly stirring, pouring the stirred liquid into a mixer with the revolving speed of 400-600 rpm, and stirring for 30-50 minutes to obtain the soap liquid; pouring the soap liquid obtained in the step 4 into a mold, and placing the mold in a vacuum drier to be dried for 20-30 hours to obtain a crude product; taking out the crude product obtained in the step 5 from the mold, and placing at the room temperature for 2-5 days to obtain the cymbopogon citratus handmade soap. The preparation method is simple in production process and ensures the cymbopogon citratus handmade soap to be comfortable and healthy to use.

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Patent File 225 Beverages from lemongrass

No. Patent Number Title Abstract
1 CN 101,926,398 Granular green tea with verbena, lemon grass and sweet orange and preparation method thereof The invention relates to a preparation method of granular green tea with verbena, lemon grass and sweet orange, which comprises the following steps of: washing lemon grass, lemon verbena and green tea; slitting; drying; selecting; sterilizing; crushing into powder with the grain diameter of 300 meshes by using an ultramicro crushing system; mixing the powder evenly; adding concentrated sweet orange juice in proportion, preparing into 2.0-3.0mm granules by using a high-efficiency rotating granulator; drying; sieving; sterilizing; and bagging. The granular green tea with verbena, lemon grass and sweet orange comprises the following components in percentage by weight: 31.5%-39.1% of lemon grass; 11.6%-18.9% of lemon verbena; 45.5% -53.2% of green tea and 3.4%-4.7% of sweet orange solids.; By the preparation method, green tea can achieve unique flavors of vanilla and sweet orange, is shaped into granules and convenient for brewing so that the efficacies of vanilla and green tea can be developed fully, moreover, the varieties and designs of the green tea can be increased to meet the demands of consumers.
2 CN 104,293,578 Lemon grass mulberry wine The invention discloses lemon grass mulberry wine which is prepared from the following raw materials in parts by weight: 500-550 parts of mulberry, 100-120 parts of huckleberry, 100-120 parts of date powder, 10-13 parts of fresh lemon grass, 10-12 parts of arabian jasmine flower, 3-4 parts of distiller yeast, 30-40 parts of wheat bran, 10-15 parts of lotus powder, 20-23 parts of cane sugar, 7-8 parts of polygonum multiflorum, and the like. The invention discloses the lemon grass mulberry wine, lemon grass, arabian jasmine flower and the like are mixed to prepare distiller yeast, the fragrant taste is achieved, the fragrance of fruit wine is improved, and as traditional Chinese medicine materials such as polygonum multiflorum, astragalus membranaceus, angelica sinensis and liquorice are mixed to be fermented, functions of blackening hair and tonifying spleen are achieved.
3 CN 104,137,886 Lemon grass tea vinegar milky tea and preparation method thereof The invention discloses a lemon grass tea vinegar milky tea which is prepared from the following raw materials in parts by weight: 100-120 parts of skimmed milk powder, 20-30 parts of white sugar, 10-15 parts of honey, 30-40 parts of broadleaf holly leaf powder, 10-15 parts of lemon-grass, 2-3 parts of boxthorn leaves, 4-5 parts of moutan bark, 7-8 parts of turmeric, 8-10 parts of hawthorn, 4-5 parts of cape jasmine, 2-3 parts of circium japonicum, 3-4 parts of serrate rabdosia herb, 1-2 parts of fructus piperis longi, 20-30 parts of nutrition powder and a defined amount of acetic bacteria. The lemon grass tea vinegar milky tea is prepared by adopting the following steps: fermenting broadleaf holly leaves, lemon grass and Chinese medicinal herbs by using acetic acid bacteria to prepare tea vinegar, and then adding the tea vinegar together with nutrition powder made from oat kernels, water chestnut leaves and barley grass powder into milky tea. The lemon grass tea vinegar milky tea is special in flavor, sour and sweet and is rich in nutrients, and has effects of tonifying the spleen and the stomach, reducing fever and causing diuresis, helping produce saliva and slake thirst, wetting the whistle and relieving cough, reducing blood pressure and losing weight, beautifying skin, and preventing and treating cancer.
4 CN 104,397,293 Lemongrass and red date tea and production process thereof The invention discloses a lemongrass and red date tea and a production process thereof. The production process comprises the steps that dry stems of lemongrass, dry leaves of the lemongrass and dry red dates are prepared, then the dry stems of the lemongrass, the dry leaves of the lemongrass, the dry red dates and Chinese wolfberries are mixed in the weight proportion of (2-3):1:(10-12):5, and the lemongrass and red date tea is obtained. The production process is simple, no food additives are added, and the lemongrass and red date tea is natural, healthy, unique in taste, aromatic and delicious and has the health care effects of refreshing, replenishing qi and nourishing blood, warming the middle, invigorating stomach, removing food retention, helping digestion, clearing heat, removing toxicity, moistening lung to arrest cough and the like.
5 CN 104,804,922 Lemongrass beer and preparation technology thereof The invention relates to lemongrass beer and a preparation technology thereof. The beer comprises the following raw materials in percent by weight: 0.55-0.72% of beer yeast, 80.25-87.5% of water, 1.2-2.4% of lemongrass extracting solution, 4-8% of glucose and 10-15% of degermed corn. The preparation technology comprises the following steps: step 1, selecting fresh lemongrass, cleaning the selected fresh lemongrass, placing the fresh lemongrass cleaned in water for extraction, filtering to obtain the lemongrass extracting solution, and refrigerating the lemongrass extracting solution in a refrigerator with the temperature of 4 DEG C for standby; step 2, weighing the raw materials according to the weight percent, smashing rice and the degermed corn and enable the smashed rice and degermed corn to pass through a screen of 80-100 meshes, placing in a mash kettle, adding water, heating at the temperature of 72-80 DEG C for 30-50 min, and filtering to obtain a filtrate; step 3, adding the lemongrass extracting solution into the filtrate, stirring, adding the beer yeast and the glucose, performing vacuum fermentation at the temperature of 5-7 DEG C for 10-18h, filtering and sterilizing, so as to obtain the lemongrass beer. The lemongrass beer has an anti-virus effect and a good market prospect.
6 CN 104,938,660 Preparation method of lemon lemongrass tea The invention provides a preparation method of lemon lemongrass tea, which comprises the following steps: picking, sunning, withering, rocking, rolling, fermenting, drying, and naturally fermenting for 10-15 months in a warehouse to obtain the lemon lemongrass tea. The preparation technology is strict, the prepared lemon lemongrass tea has the advantages of thick tea fragrance, rich mouthfeel, long storage time, and no mildew generation.
7 JPH 01,206,977 Production of lemongrass for beverage To obtain the lemongrass of good taste, enhanced in nutrient value and pharmacological effect, by mixing the chopped or crushed product from lemongrass leaves and green tea leaves, chopped or crushed product therefrom in specified proportion. CONSTITUTION:Firstly, the leaves of lemongrass such as Andropogen citratus are chopped or crushed. Thence, 100pts.wt. of the resultant chopped or crushed product is mixed with 900-50pts.wt. of chopped or crushed product from e.g., green tea leaves, thus obtaining the objective lemongrass.

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Patent File 227 Mangosteen extract

No. Patent Number Title Abstract Hits
1 WO 2016/043,524 Composition for preventing or alleviating periodontal diseases, containing, as active ingredient, mangosteen extract or α- or γ- mangosteen The present invention provides a composition for preventing, alleviating or treating periodontal diseases, containing a mangosteen extract. The composition of the present invention contains a mangosteen extract or α-mangosteen or γ-mangosteen isolated therefrom, thereby exhibiting excellent antibacterial and anti-inflammatory effects on pathogens of periodontal diseases, and thus can be widely used in medicine and food for preventing, alleviating or treating periodontal diseases.  
2 CN 1,436,786 Extraction process of mangosteen glycoside from mangosteen The extraction process of mangosteen glycoside from fresh mangosteen fruit has water as extracting solvent and includes mainly microfiltering, ultrafiltering and nano filtering. The microfiltering iswith porous filtering membrane of 0.05-0.3 micron pores; the ultrafiltering is to use hollow fiber ultrafiltering membrane for intercepting matter of molecular weight 20000-80000; and the nano filtering is to use nano filtering membrane for intercepting matter of molecular weight 100-400 or is to concentrate with RO reverse osmosis apparatus. The process is performed under low temperature condition, and this results in good product color, dissolvability, clarity and taste, less loss of active components, lowered power consumption and cost, high product yield and quality.  
3 JP 2003/231,607 Mangosteen extract and antimicrobial deodorant containing the same PROBLEM TO BE SOLVED: To obtain a mangosteen extract which does not exhibit a deep color/ color deepening by oxidation during extraction, cleaning, drying and processing processes and has excellent antimicrobial and deodorizing action in a low concentration on offensive smell/malodor caused by proliferation of harmful microorganisms, and an antimicrobial deodorant containing the same. ;SOLUTION: The mangosteen extract is obtained by immersing a mangosteen fruit in a water-containing organic solvent to give a solution, distilling away the organic solvent from the solution to give a precipitate, filtering off and/or centrifuging the precipitate and cleaning the precipitate with a liquid containing an acid and/or a reducing agent as an inhibitor for the deep color/color deepening. The antimicrobial deodorant containing the mangosteen extract is then obtained.  
4 CN 101,028,070 Mangosteen extract, its production and use A mangosteen extract in the form of red-brown paste or pink powder used for health-care food or beverage is prepared from mangosteen fruit through extracting in water or low-carbon alcohol chosen from methanol, ethanol, propanol, isopropanol and butanol, filtering, concentrating, chromatography to obtain pasty product, and drying to obtain powder product.  
5 JP 2013/107,882 Mangosteen extract To provide a mangosteen extract having high antioxidation activity. ;SOLUTION: In this mangosteen extract, the ORAC value per gram is 3,900-10,000 [mu]molTE. The mangosteen extract is obtained by a production method including the step of subjecting a raw pericarp or a defrosted frozen pericarp to short-time hot water treatment.  
6 CN 101,904,880 Mangosteen total xanthone extract and application thereof in preparation of TR3 receptor inducer The invention discloses a mangosteen total xanthone extract and a preparation method thereof and well as application in the preparation of a TR3 receptor inducer, belonging to the field of pharmaceuticals and foods. The mangosteen total xanthone extract is applied to preparing foods or medicines for preventing or treating cancers, hepatitis or atherosclerosis as the TR3 receptor inducer. The TR3 receptor inducer and pharmaceutically-acceptable vectors are mixed to prepare powders, tablets, capsules, pills, suppositories, dropping pills, enteric-coated agents, injections, syrups, emulsions, suspensions, tinctures, ointments or sprays.; Based on a mechanism that TR3 is possible to be an ideal molecular target for screening anti-tumor and cardiovascular medicines, the invention discovers and develops compounds for selectively controlling the TR3 expression approach or medicine compositions with the advanced treating characteristic and has practical meaning.  
7 US 2006/0,088,643 Neutraceutical composition containing mangosteen pericarp extract A neutraceutical beverage comprising pericarp extract from the Garcinia mangostana L. (mangosteen) plant, and juice from mangosteen fruit pulp, preferably combined with juice from at least one of four other ingredients selected from red grapes, lycium, sea buckthorn, and apple, preferably obtained from powdered extract of mangosteen pericarp and a mixture of fruit concentrate and/or powdered fruit and/or fruit extract In a preferred embodiment the neutraceutical beverage comprises mangosteen pericarp extract and juice from each of mangosteen fruit pulp, red grapes, lycium, sea buckthorn, and apple. The mangosteen pericarp extract can be obtained by a process in which mangosteen pericarp is extracted with ethanol, for example, a 50% ethanol, 50% water solution, and the extract is dried under vacuum. The beverage optionally can include one or more additional fruit juices or concentrates, or fruit or plant extracts, such as concord grape concentrate, blueberry concentrate, red raspberry concentrate, powdered green tea extract, powdered grape seed extract, and powdered grape skin extract.  
8 US 2009/0,062,378 Nutraceutical mangosteen composition Nutraceutical compositions derived from the fruit of the Garcinia mangostana L. or mangosteen plant and methods to make the same are provided. The nutraceutical mangosteen compositions employ novel combinations of mangosteen fruit pulp and pericarp, and can be additionally complemented by selected juice concentrates to yield a composition for improving general health and wellness in humans. The methods to make the nutraceutical compositions involve the use of a mixture comprising pericarp and inner pulp from whoe fruit of a Garcinia mangostana L. plant.  

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Patent File 226 Lemongrass essential oil

No. Patent Number Title Abstract
1 CN 103,330,852 Application of lemongrass oil extract in treatment of atherosclerosis. The invention relates to the field of natural medicines and in particular relates to an application of a lemongrass oil extract in treatment of atherosclerosis. Pharmacodynamic experiments show that the lemongrass oil extract can improve experimental atherosclerosis rabbit hemorheology indexes, and the lemongrass oil extract also has an antioxidant effect and can treat experimental atherosclerosis by virtue of antioxidation.
2 US 5,403,587 Disinfectant and sanitizing compositions based on essential oils The present invention provides an aqueous antimicrobial composition containing one or more essential oils which exhibit antimicrobial properties and which can be combined with a water carrier and a solubilizing or dispersing agent to form a solution or a dispersion of the essential oil in the water carrier, said essential oil exhibiting antimicrobial properties when incorporated in said water carrier.
3 US 2015/0,209,295 Essential oil microparticles and uses thereof for preventing enteric diseases The present invention relates to a microparticle containing essential palmarosa and lemongrass oils for controlling enteric diseased caused by microorganisms. More specifically, the microparticle according to the present invention can be used for controlling enteric infections caused by pathogenic bacteria in humans and animals, and can be used as an alternative to the administration of antibiotics for that purpose. The microparticle can be used in the veterinary and pharmaceutical fields and can be administered orally.
4 CN 103,361,179 Extraction method of lemongrass essential oil The invention relates to an extraction method of lemongrass essential oil, belonging to the technical field of plant essential oil extraction. According to the invention, a solvent extraction method and a low-temperature distillation method are mainly used for extraction. The method comprises the following steps: repeatedly pouring an petroleum ether solvent on the pre-extracted lemongrass; putting the lemongrass into a distiller, heating at the lower part to generate steam so as to ensure that the essential oil of the lemongrass is volatilized along with the steam; collecting and cooling the steam containing the essential oil after passing through a pipe connected with the distiller; cooling the steam into liquor, and separating according to the ratio of water to essential oil and the difference of densities. The lemongrass extractive contains multiple types of nutrient substances, and can be widely used for additives of products such as foods, cosmetics and medicines.
5 CN 103,031,213 Lemongrass dehydration method capable of preparing lemongrass essential oil incidentally The invention provides a lemongrass dehydration method capable of preparing lemongrass essential oil incidentally. The dehydration method comprises a step of drying and dehydrating the lemongrass by using a closed dryer, and also comprises a step of collecting the steam, a step of condensing the steam, a step of filtering by an ultra-filtration membrane, a step of filtering by a nano-filtration membrane and a reverse osmosis concentrating step, wherein the concentrated solution obtained after the reverse osmosis concentrating step is lemongrass essential oil, and the permeate liquid is lemongrass essence. By adoption of the method, the steam generated in the lemongrass dehydration drying process is likely to be collected and in which the contained vanilla essential oil is separated, thus the excellent economic effects of making waste profitable and making maximum use of lemongrass are achieved.
6 CN 103,333,745 Method of extracting lemongrass essential oil based on supercritical CO2 extraction technology The invention discloses a method of extracting lemongrass essential oil based on a supercritical CO2 extraction technology. The method comprises the steps of screening, drying, smashing and extracting lemongrass, wherein in the step of extracting the lemongrass, a temperature of an extraction kettle is set to be 38 DEG C; extraction pressure is 30Mpa; the extraction time is 120min; a volume flow rate of a solvent CO2 is 16L/h; during extraction, alcohol serves as an entrainer; and a mass concentration of alcohol is 70%. The method is simple to operate; a yield of the separated essential oil is high; and the method is small in equipment size, less in investment, low in energy consumption and short in time, and is an ideal method of extracting the lemongrass essential oil.
7 CN 104,893,816 Method used for refining essential oil from lemongrass The invention provides a method used for refining essential oil from lemongrass. The method comprises following steps: step 1, lemongrass is washed, dried in the air, and smashed into powder with a particle size smaller than 100 meshes; step 2, ether liquid state butane solvent is poured onto lemongrass powder for preextraction for a plurality of times, and the lemongrass powder is delivered into a distiller for distillation so as to obtain steam containing lemongrass essential oil; step 3, the steam containing lemongrass essential oil is subjected to adsorption treatment with an adsorbent; step 4, the steam delivered through the adsorbent is delivered into a cooling tower for cooling; and step 5, the steam is cooled to be a condensate liquid, and the condensate liquid is delivered into an oil-water separation tower so as to obtain lemongrass essential oil via separation. According to the method, solvent extraction and low temperature distillation are adopted for extraction, yield of lemongrass essential oil is increased, energy is saved, the method is simple, no pollution is caused by extraction processes, and oil yield is increased by about 20% compared with that of a conventional steam distillation method.
8 CN 104,928,039 Preparation method for lemongrass essential oil The invention provides a preparation method for lemongrass essential oil. The lemongrass essential oil is prepared by the following steps of 1, cleaning lemongrass leaves, pressing the lemongrass leaves in a presser, and filtering pressed liquid to obtain lemongrass filtrate; 2, sterilizing the lemongrass filtrate; 3, adding sodium chloride in an amount which is 15 percent based on the weight of the pressed liquid of lemongrass to be mixed with the sterilized lemongrass filtrate, and standing the mixed liquid for 2 days; 4, performing distillation treatment on the mixed liquid in a distiller to obtain lemongrass essential oil-containing steam; 5, cooling the steam into liquid, and feeding the condensate into an oil-water separation tower to separate the lemongrass essential oil. According to the preparation method, the lemongrass essential oil is obtained by a steam distillation method, so that the yield of the lemongrass essential oil is increased, energy resources are saved, a process is simple, fewer impurities are produced, and high quality is ensured.

Patent File 228 Mangosteen peel extract

No. Patent Number Title Abstract
1 KR 2014/0,142,871 Composition containing gamma-mangosteen for preventing or treating degenerative brain disease The present invention relates to a composition containing gamma-mangostin as an active ingredient for preventing or treating degenerative brain diseases. The gamma-mangostin of the present invention inhibits oxidative damage in neural cells and apoptosis, has an excellent anti-oxidative effect, and inhibits excitotoxicity in neural cells, activation of A[beta] peptide-induced neurotoxicity and beta-secretase so as to reduce side effects and have excellent effects for preventing nerves and suppressing the synthesis of A[beta] peptide, thereby being able to be useful for preventing or treating degenerative brain diseases including dementia.
2 CN 103,432,179 Compound mangosteen medicament and preparation process thereof The invention discloses a compound mangosteen medicament. The medicament is prepared by mixing the following raw materials in a weight ratio: 10g-60g of mangosteen and 0.5g-5g of L-aspartic acid calcium salt. The invention also provides a preparation process of the compound mangosteen medicament and the preparation process comprises the following steps of: (1) weighing mangosteen, refluxing and extracting with ethanol to prepare fluid extract; (2) preparing the fluid extract into extract powder; (3) granulating the extract powder, and uniformly mixing the granules and the L-aspartic acid calcium salt, and preparing a preparation by a conventional method.; The medicament provided by the invention can be used for treating osteoarthritis, osteoporosis and osteoarthritis complicated with osteoporosis, is safe and effective, and has the characteristics of exact curative effect, small dosage, safe administration, no toxic or side effect and the like, compared with similar medicaments.
3 US 2010/0,330,137 High bioavailability formulation of mangosteen and manufacturing process thereof The present invention relates to a pharmaceutical or dietary composition containing Mangosteen (Garcinia Mangostana pericarp) and being characterized by high bioavailability. A process for the manufacture of this composition is a further object of the present invention. In particular, the present invention relates to a composition containing Mangosteen extract and oligosaccharides in an amount ranging from 5 to 50 w/w % with respect to the Mangosteen extract or a fermented Mangosteen product and to a process for obtaining thereof.
4 CN 103,393,576 Mangosteen extract and application thereof The invention provides a mangosteen extract and application thereof, and the mangosteen extract has good whitening and anti-aging effects, can be used in cosmetics, health food and pharmaceutical fields, and particularly can be used in the cosmetics.
5 CN 1,833,665 Mangosteen peel extracts, its extraction method and medicine use An extract of mangosteen fruit peel as a new Chinese-medicinal material is prepared from the peel of mangosteen fruit through breaking, extracting in alcohol and recovering alcohol. It can be used to treat hyperlipemia, coronary heart disease, angina pectoris and myocardial ischemia.
6 WO 2013/036,210 Medical face mask coated with mangosteen shell extracts This invention is related to the medical face mask coated with mangosteen shell extracts with special and distinguishable feature in that, apart of its capacity to filter-out dust particles, the middle layer which is coated with mangosteen shell extracts has the capacity to protect against tuberculosis and other germs affecting the respiratory system. Furthermore, after use, the medical mask specified in this invention can still kill any germs that are attached on it; thereby, reducing the risk of spreading of diseases through carriers.
7 CN 101,525,328 Method for extracting alpha-mangostin from mangosteen fruit peel The invention relates to a method for extracting alpha-mangostin from a mangosteen fruit peel. The method comprises the following realization steps: (I) extracting the mangosteen fruit peel; (II) concentrating an extracting solution; mixing the extracting solution of every time and concentrating under reduced pressure to obtain a concentrated solution; (III) leaching the solution; (IV) carrying out silica gel column chromatography; (V) carrying out coarse crystallization; and (VI) carrying out recrystallization: adding a primary crystal into an organic solvent with the volume of 1 to 5 times to carry out thermal dissolution; placing the solution after finishing the thermal dissolution, reducing the temperature to a room temperature, carrying out recrystallization, and controlling the crystallization time to between 10 and 20 hours; and filtering and centrifugating a recrystallization liquid, drying the liquid in vacuum to obtain the 98 percent alpha-mangostin. The method has the advantages of simple process and short operation time.
8 CN 103,211,850 Method for extracting flavone from mangosteen skin The invention provides a method for extracting flavone from mangosteen skin. The method provided by the invention comprises the following main processes: 1, cleaning; 2, drying; 3, smashing; 4, charging; 5, carrying out ultrasonic wave extracting; 6, filtering; and 7 carrying out purification concentration. The flavone extracted by the invention is a flavonoid compound and a natural activity product widely distributed in plants, is low in molecular weight and is a plant polyphenol metabolic product; the flavone extracted by the invention is a compound of a 2-phenyl chromone structure; the flavone extracted by the invention has an extensively biological activity effect and can be frequently used for resisting oxidation, resisting ageing, eliminating free radicals, reducing blood pressure, reducing blood fat, resisting bacteria, diminishing inflammation and improving immunity; the flavone can also be widely applied to cosmetics; and use of the flavone is extensive, and the flavone is also high in price, so that great significance is produced while the flavone is extracted from the mangosteen skin.
9 CN 104,892,56 Method for extracting high-content alpha-mangostin from mangosteen skin The invention discloses a method for extracting high-content alpha-mangostin from mangosteen skin. The method comprises the following steps: (1) extracting: crushing mangosteen skin raw materials, placing the crushed mangosteen skin raw materials into an extracting device, adding an acid alcohol solvent in amount which is 4 to 5 times the weight of the mangosteen skin raw materials, placing the solution into water bath at the temperature of 85-95 DEG C, extracting for 2 to 3 times and for 1.5 to 2 hours at each time, combining the extracting liquids and filtering to obtain the filtered extracting liquid; and (2) performing chromatography: allowing the filtered liquid to pass through a neutral alumina chromatographic column, performing gradient elution, collecting the eluent, concentrating the eluent under reduced pressure until no alcohol taste exists, standing the eluent at the temperature of 4 DEG C for more than or equal to 4 hours until crystallization, centrifuging, and taking the precipitate to obtain the finished product. The method has the advantages of few steps, low time consumption, little reagent dosage and low cost, and is simple to operate and easy to control. By the method, the alpha-mangostin with the highest content of more than or equal to 99.0% can be obtained. The method is suitable for industrialized production.
10 CN 101,816,687 Method for extracting mangosteen pericarp anthocyanin and application thereof in preparing anti-inflammatory drugs The invention belongs to the field of natural medicinal chemistry, in particular to separation and extraction of natural anti-inflammatory drug molecules and an application thereof. The method comprises the following steps of extracting by acidic ethanol, decompressing and concentrating, adding water for dissolving, loading a sample in XAD-7 macroporous resin, eluting, collecting and concentrating, freeze-drying to extract the mangosteen pericarp anthocyanin. Experimental results show that mouse peritoneal fluid neutrophil exudation can be effectively inhibited after the mangosteen pericarp anthocyanin is injected into caudal vein of the mouse, the inhibition ratios are respectively 34%, 77% and 94% while the dosages are respectively 0.01, 0.1 and 1mg/ml.; A laminar experiment using an in-vitro simulated capillary proves that the adhesion inhibition ratios of the mangosteen pericarp anthocyanin on neutrophil are respectively 45%, 71% and 89% while the dosages are respectively 0.01, 0.1 and 1mg/ml. Therefore, the anti-inflammatory activity of the mangosteen pericarp anthocyanin is proved, and the mangosteen pericarp anthocyanin as a novel anti-inflammatory drug has good application prospect.
11 CN 105,130,944 Method for extracting procyanidine from mangosteen shells The invention relates to a method for extracting procyanidine from mangosteen shells. According t to the method, mangosteen shells serve as raw materials, and procyanidine is extracted through combination of an enzymic preparation and a solvent. The preparing method comprises the following steps of preparing materials, preparing a buffering solution, preparing an enzyme solution, casting the materials, carrying out enzymolysis, carrying out extraction and forming a finished product. The obtained procyanidine product can be applied to natural pigment food additives, medicine healthcare products with the anti-oxidation effect, cosmetics and other industries.
12 CN 104,435,019 Novel pharmaceutical application of mangosteen shell extract The invention discloses a novel pharmaceutical application of a mangosteen shell extract. The mangosteen shell extract is applied to preparation of the following products: (1) a product for preventing and/or treating the Parkinson disease; (2) a product for preventing and/or treating the degenerative change of dopaminergic neuron dendrites of a patient suffering from the Parkinson disease; (3) an oxidative-stress-resistant product; and (4) a product for preventing and/or treating oxidative stress of the Parkinson disease. Pharmacodynamic experiments prove that the mangosteen shell extract can be used for recovering (parts of) dopaminergic neuron dendrites of a nematode model suffering from the a30p Parkinson disease, and can also be used for inhibiting the level of reactive oxygen in the nematode model suffering from the Parkinson disease induced by rotenone. Furthermore, the mangosteen shell extract is proved to have relatively good Parkinson disease resistance and oxidative stress resistance.